Choose Your Friends Wisely

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Choose Your Friends Wisely

When we think of the word ‘‘contagious,’’ we often think of something negative, like the flu. But transmitted diseases aren’t the only thing that can quickly spread within a society—certain feelings, emotions, and behaviors can be easier to catch than the common cold. Does seeing others laugh or yawn make you want to do it too? You’re definitely not alone—‘‘behavioral contagion,’’ or the tenden...

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Improving insulin resistance in obese youth: choose your measures wisely.

OBJECTIVE The purpose of this investigation was to compare the homeostasis model assessment of insulin resistance (HOMA-IR) to more direct measures of insulin action before and after lifestyle interventions in obese Latino youth. STUDY DESIGN Eleven obese Latino boys (age 15.1 ± 1.6 years, body mass index (BMI) percentile 97.3 ± 3.5%) and twenty obese Latina girls (age 14.7 ± 1.8 years, BMI p...

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Choose Early or Choose Wisely - A Chinese Restaurant Game Approach

Agents in a network often face situations requiring them to make decisions without sufficient information. In such situations, they may postpone their decisions in order to observe and collect more information through learning from other agents. In this paper, we discuss the advantages of the postponement strategy from a gametheoretic perspective. We propose an extension to Chinese Restaurant G...

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Choose and Use Your Chemical Probe Wisely to Explore Cancer Biology

Small-molecule chemical probes or tools have become progressively more important in recent years as valuable reagents to investigate fundamental biological mechanisms and processes causing disease, including cancer. Chemical probes have also achieved greater prominence alongside complementary biological reagents for target validation in drug discovery. However, there is evidence of widespread c...

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Choose Your Label Wisely: Water-Soluble Fluorophores Often Interact with Lipid Bilayers

Water-soluble organic fluorophores are widely used as labels in biological systems. However, in many cases these fluorophores can interact strongly with lipid bilayers, influencing the interaction of the target with the bilayer and/or leading to misleading fluorescent signals. Here, we quantify the interaction of 32 common water-soluble dyes with model lipid bilayers to serve as an additional c...

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ژورنال

عنوان ژورنال: Cell

سال: 2017

ISSN: 0092-8674

DOI: 10.1016/j.cell.2017.03.037